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生化试剂
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中文名称

N-(32-亚油酰氧基-邻苯二甲t酰基)-鞘氨醇-D9

英文名字
N-(32-Linoleoyloxy-dotriacontanoyl)-sphingosine-D9
供应商
Matreya
产品货号
2208-1
产品报价
¥9537/1mg
产品说明书
购买方式
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产品新闻
背景资料
This product is a high purity omega-esterified ceramide that is ideal as a standard and for studies involving skin-barrier lipids. Omega-esterified ceramides are found almost exclusively in the epidermal layer, especially the stratum corneum. The stratum corneum is the outermost cellular layer of the epidermis and functions as the permeability barrier in mammals. It contains 12 extractable ceramide fractions containing sphingosine, 6-hydroxysphingosine, dihydrosphingosine and phytosphingosine bases.1,2 The omega-esterified ceramides are formed from glucosylceramide and sphingomyelin in special lamellar bodies in epidermal cells from which they are excreted into the extracellular domain of the outermost cell layer of the epidermis. Mammalian skin contains significant amounts of sphingolipids (as much as 50% of the total lipids), particularly very long chain linoleoyl esterified ceramide and glucosylceramide (also called O-acylceramide and O-acylglucosylceramide). These lipids, which are mostly found in the extracellular domains, are vital to the water permeability barrier to prevent lethal loss of water and pathogen invasion. The omega-esterified ceramides can be covalently bound to proteins of the cornified envelope where they form a hydrophobic layer. A deficiency of linoleoyl omega-esterified ceramides is strongly correlated with skin diseases such as psoriasis and atopic dermatitis.3
产品描述
EOS Ceramide, deuterated|O-acylceramide, deuterated
产品形式
该N-(32-亚油酰氧基-邻苯二甲t酰基)-鞘氨醇-D9产品为固体形式
保存建议
对于本产品,我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后,我们建议在-20℃温度下冷冻保存,溶解使用说明请参考本品说明书。
其他
Matreya LLC是一家脂质生化公司,致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富,生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体(生育酚和生育三烯酚)。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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