Lysine-specific demethylase 1(LSD1) is also known as AOF2, is a nuclear amine oxidase. LSD1 contain a Swirm domain, a FAD-binding motif and an amine oxidase domain that can act as a histone demethylase as well as transcription cofactor. LSD1 activity is inhibited by the amine oxidase inhibitors pargyline, deprenyl, clorgyline and tranylcypromine
应用类型
Western blotting (2-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 127of rat LSD1/AOF2
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的LSD1/AOF2蛋白发生免疫反应
保存建议
提供的100 ug LSD1/AOF2抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该LSD1/AOF2抗体产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融.